inhibiting aggregate formation in more than 80% in TTR L55P-expressing cells
Tos-PEG6-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs
Smiles: OC(=O)CCCN1CCC(CC1)O[C@@H](C1=CC=C(Cl)C=C1)C1=CC=CC=N1
Pymetrozine is a feeding inhibitor of Homoptera
CHMFL-PI3KD-317 Size:Contact [email protected] for quotation inhibiting aggregate formation in moreCHMFL PI3KD 317 is a highly potent, selective and orally active PI3K inhibitor, with an IC50 of 6 nM, and exhibits over 10 1500 fold selectivity over other class I, II and III PIKK family isoforms, such as PI3K (IC50, 62. 6 nM), PI3K (IC50, 284 nM), PI3K (IC50, 202. 7 nM), PIK3C2A (IC50, >10000 nM), PIK3C2B (IC50, 882. 3 nM), VPS34 (IC50, 1801. 7 nM), PI4KIIIA (IC50, 574. 1 nM) and PI4KIIIB (IC50, 300. 2 nM). CHMFL PI3KD 317 inhibits PI3K mediated Akt