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while it failed to displace [(3)H]LY341495 (a competitive mGlu2/3 receptor antagonist)
Formula: C22H37Cl3N4O
7aR)-7-({[2
InChi: InChI=1S/C16H16N2O6/c19-12(20)7-17-15(22)13-14(21)10-3-1-2-4-11(10)18(16(13)23)24-8-9-5-6-9/h1-4
L-701324 tone isopropyl while it failed to displaceL 701324 is an orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor. Target: NMDA ReceptorL 701324 is a potent, active anticonvulsant with a reduced propensity to activate mesolimbic dopaminergic systems in rodents. L 701324 exhibits a beneficial action in the animal model of parkinsonian rigidity, but not that of parkinsonian akinesia. L 701324 (2. 5 40 mg kg, i. p.) dose
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