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The clinically used photosensitizer Verteporfin (VP) inhibits YAP-TEAD and human retinoblastoma cell growth in vitro without light activation
there is no significant change in expression of Bcl-2 and Bax proteins
60 μg • h/ml or higher for concentration-time curve over 24 h (AUC24h)
Formula: C34H42IN5S
Biotin-PEG8-NHS ester 6766 The clinically used photosensitizer VerteporfinBiotin PEG8 NHS ester is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2143968 03 8 Molecular Weight: 764. 88 Formula: C33H56N4O14S Chemical Name: 2,5 dioxopyrrolidin 1 yl 1 {5 [(3aS,4S,6aR) 2 oxo hexahydro 1H thieno[3,4 d]imidazol 4 yl]pentanamido} 3,6,9,12,15,18,21,24 octaoxaheptacosan 27 oate Smiles: O=C1N[C@H]2CS[C@@H](CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON3C(=O)CCC3=O)[C@H]2N1