ABC294640 - CAS# 915385-81-8 Catalog No.:M6465-10 Formula: C12H15N3O2

Name: ABC294640 - CAS# 915385-81-8 Catalog No.:M6465-10 Formula: C12H15N3O2
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Description

Formula: C12H15N3O2

LKB1-activated NUAK1 kinase

33)/t20-/m0/s1

PKC-iota inhibitor 1

ABC294640 - CAS# 915385-81-8 Catalog No.:M6465-10 Formula: C12H15N3O2ABC294640, also known as Opaganib, CAS No. 915385 81 8, is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase 2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preventing the phosphorylation of the pro apoptotic amino alcohol sphingosine to sphingosine 1 phosphate (S1P), the lipid mediator that is pro survival and critical for

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