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6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl]-1-phenylethan-1-one
peripherally restricted angiotensin II type 2 receptor (AT2R) antagonist
CAS Number: 4542-23-8
Adaptor associated kinase 1 (AAK1) is a member of the Ark1/Prk1 family of serine/threonine kinases
Hydroxysafflor yellow A Size:Contact [email protected] for quotation 6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl]-1-phenylethan-1-oneHydroxysafflor yellow A is a flavonoid derived and isolated from traditional Chinese medicine Carthamus tinctorius L., possesses anti tumor activity. IC50 value: Target: in vitro: HYSA could inhibit LPS induced VSMCs proliferation and migration, accompanied by the downregulated levels of several key pro inflammatory cytokines, including TNF , IL 6, and IL 8. We further showed that HYSA inhibited LPS induced upregulation of TLR 4 expression as well as
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