Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK)
Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC)
24(7):696-8
MYCi975 significantly inhibits tumor growth and increases survival in the MycCaP allograft model with animals tolerating a 100 mg/kg/day i
Abiraterone metabolite 1 Catalog No.:M20605-C Chemically Induced Degradation of AnaplasticAbiraterone metabolite 1 is a 5 reduced metabolite of abiraterone. Abiraterone, a steroidal drug, inhibits CYP17A1, blocks androgen synthesis and prolongs survival in prostate cancer. Product information CAS Number: 1940176 03 3 Molecular Weight: 351. 52 Formula: C24H33NO Chemical Name: (3aS,3bR,5aR,7S,9aS,9bS,11aS) 9a,11a dimethyl 1 (pyridin 3 yl) 3H,3aH,3bH,4H,5H,5aH,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH cyclopenta[a]phenanthren 7 ol Smiles: