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EN4 directly targets MYC in cells and reduces MYC and MAX thermal stability
Tail vein injection or oral gavage delivery of SH5-07 or SH4-54 inhibits growth of 90-150 mm3 established subcutaneous mouse xenografts of human glioma (U251MG) and breast (MDA-MB-231) tumors that harbor aberrantly-active Stat3
Treprostinil preserves the sinusoidal endothelial cell lining and reduces platelet deposition early post-transplantation compared to placebo
Lithocholic acid-d4 (3α-Hydroxy-5β-cholanic acid-d4) is the deuterium labeled Lithocholic acid
Indomethacin-D4 10844 EN4 directly targets MYC inIndomethacin D4 (Indometacin D4) is a deuterium labeled Indomethacin. Indomethacin is a potent, blood brain permeable and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX 1 and COX 2, respectively, in CHO cells. Indomethacin disrupts autophagic flux by disturbing the normal functioning of lysosomes. Product information CAS Number: 87377 08 0 Molecular Weight: 361. 81 Formula: C19H16ClNO4 Chemical Name: 2 {1 [4
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