SIS3 HCl - CAS# 521984-48-5 225 Modulation of innate and adaptive

Modulation of innate and adaptive immune responses by tofacitinib (CP-690

Yamamoto K

Molecular Weight: 509

pii: S2213-1779(14)00379-5

SIS3 HCl - CAS# 521984-48-5 225 Modulation of innate and adaptiveSIS3 HCl, CAS No. 521984 48 5, a novel specific inhibitor of Smad3, inhibits TGF and activin signaling by suppressing Smad3 phosphorylation without affecting the MAPK p38, ERK, or PI3 kinase signaling pathways. Product information CAS Number: 521984 48 5 Molecular Weight: 489. 99 Formula: C28H28ClN3O3 Synonym: (E) SIS3 Chemical Name: (2E) 1 (6,7 dimethoxy 1,2,3,4 tetrahydroisoquinolin 2 yl) 3 {1 methyl 2 phenyl 1H pyrrolo[2,3 b]pyridin 3 yl}prop 2 en