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VHL ligand 3
CCT137690 efficiently inhibits histone H3 and TACC3 phosphorylation (Aurora B and Aurora A substrates
GW806742X shows inhibition of VEGF induced proliferation of HUVECs with an IC50 of 5 nM
Reprod Fertil Dev
Phenamil methanesulfonate Catalog No.:M13338-10 VHL ligand 3Phenamil methanesulfonate, an analog of Amiloride (HY B0285), is a more potent and less reversible epithelial sodium channel (ENaC) blocker with an IC50 of 400 nM. Phenamil methanesulfonate is also a competive inhibitor of TRPP3 and inhibits TRPP3 mediated Ca2+ transport with an IC50 of 140 nM in a Ca2+ uptake assay. Phenamil methanesulfonate is an intriguing small molecule to promote bone repair by strongly activating BMP signaling pathway. Phenamil