![MS31 trihydrochloride tenol sodium 4-dimethylpentanamido]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoic acid](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M13973_1631088307.gif?v=1631088309)
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4-dimethylpentanamido]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoic acid
with an IC50=0
Solubility: DMSO: 53 mg/mL(201
InChi: InChI=1S/C24H44O10/c1-5-7-26-9-11-28-13-15-30-17-19-32-21-22-33-20-18-31-16-14-29-12-10-27-8-6-23(25)34-24(2
MS31 trihydrochloride tenol sodium 4-dimethylpentanamido]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoic acidMS31 trihydrochloride is a potent, highly affinity and selective fragment like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 trihydrochloride potently inhibits the interactions between SPIN1 and H3K4me3 (IC50=77 nM, AlphaLISA; 243 nM, FP). MS31 trihydrochloride selectively binds Tudor domain II of SPIN1 (Kd=91 nM). MS31 trihydrochloride potently inhibits binding of trimethyllysine containing peptides to SPIN1, and is not toxic to
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