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PF-3758309 dihydrochloride ergocristine mesylate 39 mg/mL(198

SKU: 74916591218

4.6
USD119.00 USD157.00

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Description

39 mg/mL(198

by upstream kinases

InChi: InChI=1S/C21H11NO5S/c23-12-2-5-16-18(8-12)26-19-9-13(24)3-6-17(19)21(16)15-4-1-11(22-10-28)7-14(15)20(25)27-21/h1-9

CAS Number: 298-93-1

PF-3758309 dihydrochloride ergocristine mesylate 39 mg/mL(198PF 3758309 dihydrochloride is a potent, orally available, and reversible ATP competitive inhibitor of PAK4 (Kd= 2. 7 nM; Ki=18. 7 nM). PF 3758309 dihydrochloride has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation. Product information Molecular Weight: 563. 55 Formula: C25H32Cl2N8OS Chemical Name: N [(1S) 2 (dimethylamino)

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