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78(6):1143-1150
Smiles: NC(=O)C1C=C[N+](CC2CS[C@@H]3[C@H](NC(=O)[C@@H](C4C=CC=CC=4)S(=O)(=O)O[Na])C(=O)N3C=2C([O-])=O)=CC=1
Chemical Name: dimethyl(2-{1-[(2
InChi: InChI=1S/C71H81N11O9/c1-44(2)63(71(91)81-61(39-47-22-10-5-11-23-47)67(87)77-58(64(74)84)41-49-29-32-50-24-12-13-25-51(50)36-49)82-66(86)57(28-16-17-35-72)76-70(90)62(42-52-43-75-56-27-15-14-26-54(52)56)80-69(89)60(40-48-30-33-53(83)34-31-48)79-68(88)59(38-46-20-8-4-9-21-46)78-65(85)55(73)37-45-18-6-3-7-19-45/h3-15
APG-115 Size:Contact [email protected] for quotation 78(6):1143-1150APG 115 (AA 115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3. 8 nM and 1 nM, respectively. APG 115 blocks the interaction of MDM2 and p53 and induces cell cycle arrest and apoptosis in a p53 dependent manner. Product information CAS Number: 1818393 16 6 Molecular Weight: 642. 59 Formula: C34H38Cl2FN3O4 Chemical Name: 4 {[(3'R,4'S,5'R) 6'' chloro 4' (3 chloro 2 fluorophenyl) 1' ethyl 2'' oxo 1'',2''
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