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65(5):435-44
Functionalized cereblon ligand for PROTAC® research and development
also known as Apoptosis Activator 2
SF-1670 (500 nM)–pretreated neutrophils show nearly 70% higher (maximal) superoxide production than untreated neutrophils
Capmatinib HCl hydrate - CAS# 1865733-40-9 Laurdan 65(5):435-44Capmatinib HCl hydrate, CAS No. 1865733 40 9, also known as INCB28060 and INC280, is an orally bioavailable inhibitor of the proto oncogene c Met (hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c Met inhibitor INC280 selectively binds to c Met, thereby inhibiting c Met phosphorylation and disrupting c Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c Met protein or