Pay in 4 interest-free payments of $32.25 Learn more
Ships within 48 hours · Estimated delivery Aug 4 - Aug 9
PSI-7977 produces anti-HCV activity with EC90 values 0
Chemical Name: N-(2
It inhibits HDAC3 with IC50 of 289 nM
856243-80-6
IRE-3 - IRE1a Modulator. CAS# 1414938-21-8 60319 PSI-7977 produces anti-HCV activity withIRE 3, CAS No. 1414938 21 8, is a highly potent and selective small molecule modulator of IRE1. Under endoplasmic reticulum stress, unfolded protein accumulation leads to activation of the endoplasmic reticulum transmembrane kinase endoRNase (RNase) IRE1. IRE1 oligomerizes, autophosphorylates and initiates splicing of XBP1 mRNA, thus triggering the unfolded protein response (UPR). Interestingly, IRE 3 inhibits the XBP1 mRNA splicing through binding to
US$ 1649.99
US$ 225.00
US$ 312.50
US$ 112.50
US$ 170.00
US$ 1649.99
US$ 1049.50
US$ 250.00
US$ 3849.99
US$ 425.00
US$ 175.00
US$ 350.00