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TRIM24-C34 was used at 10 µM final concentration in various in vitro assays
54(17):6139-50
rather than directly by removing iron from the active site
1007/s12020-015-0590-1
MLN-9708 - CAS# 1239908-20-3 60262 TRIM24-C34 was used at 10MLN 9708, also known as ixazomib citrate, CAS No. 1239908 20 3, is a prodrug of Ixazomib (MMLN 2238). MLN 9708 is an orally bioavailable second generation proteasome inhibitor (PI) with potential antineoplastic activity. MLN 9708, after hydrolyzing to pharmacologically active MLN2238 (ixazomib), is a next generation proteasome inhibitor with demonstrated preclinical and clinical antimyeloma activity. MLN 9708, compared with bortezomib, has improved