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228(1-3):e25-7
Multitargeted tyrosine kinase inhibitor DCC-2036 may exhibit more potent activity against T315I Bcr-Abl gatekeeper mutant kinases than other Bcr-Abl kinase inhibitors
a guanidine derivative
05) attenuates the pressor response to angiotensin-II in rats
2-fluoro Palmitic Acid Catalog No.:M22174-C 228(1-3):e25-72 fluoropalmitic acid inhibits sphingosine biosynthesis and long chain acyl CoA synthetase . The length of the carbon chain of the fatty acid species defines the substrate specificity for the different acyl CoA synthetases (ACS). Mammalian long chain acyl CoA synthetases (ACSL) activate fatty acids with chain lengths of 12 to 20 carbon atoms. The long chain acyl CoA synthetase mRNA is expressed virtually in heart, liver, and epididymal adipose tissues