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ARC 239 dihydrochloride 98198 4-tetrahydroquinazolin-2-one

SKU: 83586369273

4.2
USD119.00 USD159.00

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Description

4-tetrahydroquinazolin-2-one

InChiKey: ULSUXBXHSYSGDT-UHFFFAOYSA-N

In a rat PK study

Yamaguchi K

ARC 239 dihydrochloride 98198 4-tetrahydroquinazolin-2-oneARC 239 dihydrochloride is a selective antagonist of 2B adrenoceptor with pKD value of 8. 8 . 2B adrenoceptor is a G protein coupled receptor. 2 adrenergic receptors include three subtypes: 2A, 2B and 2C, which play an important role in regulating neurotransmitter release from adrenergic neurons in the central nervous system and from sympathetic nerves. ARC 239 dihydrochloride is a selective 2B adrenoceptor antagonist. In rat brain, ARC 239 inhibited

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