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Cilomilast reduces TLR4 expression
6H-pyrido[2
HS-173 induced cell cycle arrest at the G(2)/M phase and apoptosis
InChi: InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3
Fedratinib hydrochloride hydrate ((2S)-1 2-propanediol hydrate) Cilomilast reduces TLR4 expressionFedratinib hydrochloride hydrate (TG 101348 hydrochloride hydrate) is a potent, selective, ATP competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35 and 334 fold selectivity over JAK1 and JAK3, respectively. Fedratinib hydrochloride hydrate induces cancer cell apoptosis and has the potential for myeloproliferative disorders research. Product information CAS Number:
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