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Smiles: CC1(C)CCC2(C(C1)C1=CCC3C(C)(CCC4C(CO)(CO)C(OC5OC(CO)C(O)C(O)C5O)C(O)CC43C)C1(C)CC2O)C(=O)OC1OCC(O)C(O)C1OC1OC(C)C(OC2OCC(O)C(OC3OCC(O)(CO)C3O)C2O)C(O)C1O
CAS Number: 244192-94-7
Minim Invasive Ther Allied Technol
Molecular Weight: 359
SAR-100842 13341 Smiles: CC1(C)CCC2(C(C1)C1=CCC3C(C)(CCC4C(CO)(CO)C(OC5OC(CO)C(O)C(O)C5O)C(O)CC43C)C1(C)CC2O)C(=O)OC1OCC(O)C(O)C1OC1OC(C)C(OC2OCC(O)C(OC3OCC(O)(CO)C3O)C2O)C(O)C1OSAR 100842 is a lysophaphatidic acid 1 (LPA1 Edg 2) receptor inhibitor. SAR 100842 (Compound Example 14) is an Edg 2 receptor inhibitor extracted from patent WO2009135590A1, has an IC50 of <0. 1 M. SAR 100842 (SAR100842) is a lysophaphatidic acid receptor 1 (LPA1) inhibitor, which can be used for the treatment of systemic sclerosis and related fibrotic diseases. In LPAR1 based in vitro inhibition of LPA stimulated Ca2+ flux in a cell based assay, SAR
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