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Sephin1 safely and selectively inhibited a regulatory subunit of protein phosphatase 1 in vivo
Formula: C25H27F4N3O3S
Chemical Name: N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide
Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad
PFK-015 (UK-453061) Sephin1 safely and selectively inhibitedPFK 015 is a potent inhibitor of PFKFB3. The preliminary results in a U87GM xenograft model have shown that PFK 015 has comparable activity to Temozolomide. PFK 015 inhibits glucoseuptake by tumors. Product information CAS Number: 4382 63 2 Molecular Weight: 260. 29 Formula: C17H12N2O Synonym: PFK015 PFK 015 Chemical Name: (2E) 1 (pyridin 4 yl) 3 (quinolin 2 yl)prop 2 en 1 one Smiles: O=C( C=C C1=CC=C2C=CC=CC2=N1)C1C=CN=CC=1 InChiKey: UJJUKZPBUMCSJZ