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CKD-581 increased the acetylation of target molecules by inhibiting class I-II HDACs in lymphoma cells
FB23 inhibits the proliferation of NB4 and MONOMAC6 cells
1-2H3/i9D2
In A121(p) cells
IMP-1088 lohexenyl Cy7 CKD-581 increased the acetylation ofIMP 1088 is a potent human N myristoyltransferases NMT1 and NMT2 dual inhibitor with IC50s of <1 nM for HsNMT1 and HsNMT2. IMP 1088 has a Kd of <210 pM for HsNMT1. IMP 1088 efficiently blocks rhinovirus replication by blocking rhinovirus virus encoded protein (VP0) N myristoylation. IMP 1088 protects host cells from the cytotoxic effects of viral infection. Product information CAS Number: 2059148 82 0 Molecular Weight: 453. 53 Formula: C25H29F2N5O
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