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CAS Number: 1038988-11-2
by combining the antibiotic with SPR741 but that potentiation of intrinsic resistance due primarily to efflux may be limited
In Dahl salt-sensitive hypertensive (DS) rats
45(10):1626-32
N-(3-hydroxyphenyl)-Arachidonoyl amide isqualic acid CAS Number: 1038988-11-2IC50: 2 M N (3 hydroxyphenyl) Arachidonoyl amide, also known as 3 HPAA, is an analog of AM404 (N (4 hydroxyphenyl) arachidonoyl amide), a selective inhibitor of carrier mediated transport of arachidonoyl ethanolamide. 3 HPAA, metabolized by both cyclooxygenase (COX) 1 and COX 2, is an irreversible and selective inhibitor of COX 2 with an IC50 value of 2 M. 3 HPAA can be efficiently oxygenated to prostaglandin and hydroxyeicosatetraenoate products by
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