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Ro 25-6981 maleate Catalog No.:M9288-2 2 substrates of this enzyme

SKU: 91630448264

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Description

2 substrates of this enzyme

The lethality of OSU-03012 is attenuated in protein kinase R-like endoplasmic reticulum kinase-/- cells

GSK591 inhibits the symmetric arginine methylation of SmD3 with EC50 = 56 nM

Norimatsu Y

Ro 25-6981 maleate Catalog No.:M9288-2 2 substrates of this enzymeRo 25 6981 is a highly potent and selective blocker of N methyl D aspartate receptors containing the NR2B subunit. Ro 25 6981 inhibited 3H MK 801 binding to rat forebrain membranes in a biphasic manner with IC50 values of 0. 003 microM and 149 microM for high (about 60%) and low affinity sites, respectively. NMDA receptor subtypes expressed in Xenopus oocytes were blocked with IC50 values of 0. 009 microM and 52 microM for the subunit combinations

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