TBA-354 Catalog No.:M8471-2 Salirasib reduces phosphorylation of S6K

Salirasib reduces phosphorylation of S6K but not of ERK in the TSC2-null ELT3 cells

Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat

mineralocorticoid

is a macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro

TBA-354 Catalog No.:M8471-2 Salirasib reduces phosphorylation of S6KTBA 354, also known as SN31354, is a potent anti tuberculosis drug candidate. TBA 354 is narrow spectrum and bactericidal in vitro against replicating and nonreplicating Mycobacterium tuberculosis, with potency similar to that of delamanid and greater than that of PA 824. TBA 354 maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug sensitive and drug resistant isolates. TBA 354 is a promising