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The clinically used photosensitizer Verteporfin (VP) inhibits YAP-TEAD and human retinoblastoma cell growth in vitro without light activation
48 μg/mL for normal mammary epithelial cells (MCF-10A)
HLI373 increases p53 and Hdm2 protein levels in cells
Smiles: C[C@]12CCC(=O)N[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@H](CC[C@H]21)C(=O)NC1=CC(=CC=C1C(F)(F)F)C(F)(F)F
SNT-207707 Catalog No.:M20012-C The clinically used photosensitizer VerteporfinSNT 207707 is a selective, potent and orally active melanocortin MC 4 receptor antagonist with an IC50 of 8 nM (binding) and 5 nM (function) on the MC 4 receptor. Product information CAS Number: 1064662 40 3 Molecular Weight: 550. 18 Formula: C32H44ClN5O Chemical Name: 2 (4 cyanophenyl) N,N bis(3 methylbutyl) 3 [3 (pyrrolidin 1 yl)propyl]imidazo[1,2 a]pyridine 6 carboxamide hydrochloride Smiles: Cl.
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