Vandetanib - CAS# 443913-73-3 CRABP-II Degrader-1 Smiles: OC(=O)C1=CC(=CC=C1N1C[C@H](CC1)OCC1=CC=CC=N1)C(F)(F)F

Smiles: OC(=O)C1=CC(=CC=C1N1C[C@H](CC1)OCC1=CC=CC=N1)C(F)(F)F

Formula: C25H34ClFN4O

Smiles: CC1C=C(NN=1)NC1C=C(CN2CCOCC2)C2=NC(C)=C(CC3=CC=C(Cl)C=C3F)N2N=1

and reticulocyte count

Vandetanib - CAS# 443913-73-3 CRABP-II Degrader-1 Smiles: OC(=O)C1=CC(=CC=C1N1C[C@H](CC1)OCC1=CC=CC=N1)C(F)(F)FVandetanib is an orally bioavailable 4 anilinoquinazoline. Vandetanib selectively inhibits the tyrosine kinase activity of vascular endothelial growth factor receptor 2 (VEGF2), thereby blocking VEGF stimulated endothelial cell proliferation and migration and reducing tumor vessel permeability. This agent also blocks the tyrosine kinase activity of epidermal growth factor receptor (EGFR), a receptor tyrosine kinase that mediates tumor cell