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61 μM for full length USP7 and USP7 catalytic domain
but the dose-response curve is not linear for NVP-ACC789
InChi: InChI=1S/C21H23FN6O6S/c1-2-33-14-5-3-4-13(22)12(14)7-6-11-9-28(20-16(11)19(23)25-10-26-20)21-18(30)17(29)15(34-21)8-27-35(24
(2015) Science
EPI-001 - CAS# 227947-06-0 Size:10mg solid 61 μM for full lengthEPI 001, a selective inhibitor of Androgen Receptor (AR), targets transactivation unit 5 (Tau 5) of the AR. EPI 001 can inhibit transactivation of the AR amino terminal domain (NTD), with an IC50 of ~6 M. EPI 001 is also a selective modulator of PPAR. EPI 001 is active against castration resistant prostate cancer. Product information CAS Number: 227947 06 0 Molecular Weight: 394. 89 Formula: C21H27ClO5 Chemical Name: 3 (4 {2 [4 (3 chloro 2
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